HONDROGARD® is contraindicated during pregnancy and lactation.
Know the Difference: How to tell pneumonia from flu?
Distinguishing between influenza, acute respiratory infections and pneumonia is difficult enough these days. Viruses and bacteria are constantly mutating and becoming more and more resistant to the various drugs on the market.
Their symptoms are similar, making it difficult to diagnose and choose the right treatment. However, each disease needs to be treated differently. That's why it's important to know the difference between the flu, acute respiratory infections, and pneumonia. Often people ignore the symptoms and don't see a doctor while a life-threatening illness develops.
The information on this website should not be used for self-medication and self-diagnosis. In case of exacerbation of symptoms, the doctor should be asked to conduct diagnostic tests, make a diagnosis and select appropriate treatment.
What is acute respiratory infection?
ARI is an acute respiratory viral infection that affects the respiratory organs. It is caused by a virus that spreads very quickly through airborne droplets (coughing, sneezing), through direct contact with the sick person (shaking hands), or through shared household items and food.
- Sore throat or scratchy throat (usually starts at the same time as the cough).
- Increased fatigue, weakness.
- Insomnia (if the fever is high).
- Headaches (not always present - usually with fever and complications such as sinus or tonsillitis).
- Sometimes swollen lymph nodes.
- Influenza or parainfluenza viruses.
- adenoviruses.
- reoviruses.
- rhinoviruses.
pharmacokinetics
Absorption. After the injection, Cmah of drug in plasma is reached after 1 hour and then gradually decreases over 2 days. After a single intra-articular administration at a dose of 200 mg Cmah of chondroitin sulfate in the plasma after 1-2 hours and is 52.5-86.9 ng/ml.
distribution. After injection, chondroitin sulfate is rapidly distributed. It is detected in significant concentrations in the blood as early as 30 minutes after the injection. Chondroitin sulfate accumulates mainly in articular cartilage. The synovial membrane does not represent an obstacle to the penetration of the preparation into the articular cavity. Experiments show that 15 minutes after the I/m injection, chondroitin sulfate is in the synovial fluid, and then penetrates into the articular cartilage, where its Cmah reached after 48 hours. After intra-articular administration, chondroitin sulfate is retained in joint tissue and gradually released into the bloodstream.
elimination. t1/2 with intra-articular injection is 2.5 hours.
contraindications
Hypersensitivity to the product or to any of the excipients listed under 'Composition';
bleeding and bleeding tendency;
presence of an active inflammatory or infectious process in the joint, presence of an active skin disease or skin infection in the area to be injected (intra-articular injection);
pregnancy (currently no data on the safety of the drug);
lactation (currently no data on the safety of the drug);
Child and young person (under 18 years of age).
Dependence on gabapentin
The rapid increase in gabapentin dependence is explained by the rapid increase in the body's resistance to certain doses of the drug. The desired effect is absent and a withdrawal syndrome occurs in full force, forcing the addict to increase the dose.
overdose
As with any drug, high doses of gabapentin can lead to overdose. The reaction depends on the dose and is individual: some experience a more severe gastrointestinal reaction, others experience cardiac and vascular reactions, still others may fall into a coma. In general, the symptoms of an overdose are as follows:
At a very high dose, death is possible, especially in combination with alcoholic beverages.
Gabapentin poisoning: first aid
In the event of an overdose, the first thing to do is to keep vital functions under control. It is imperative to call an ambulance. First aid measures are gastric lavage and taking sorbents. There is no antidote for gabapentin. Treatment is primarily symptomatic, but if necessary, inpatient hemodialysis is also possible. In some cases, resuscitation measures may be necessary.
Article by Knoobloh Expert Ekaterina Sergeevna A medical psychologist with 10 years of experience working with addicts in outpatient and inpatient rehabilitation programs. Read the article: Psychological...
Seeks
Drug withdrawal or withdrawal syndrome can also occur in people taking gabapentin for therapeutic purposes, and even more so in people dependent on drugs. Withdrawal syndrome is characterized by such phenomena as fluctuations in blood pressure and body temperature, severe joint, muscle and headaches. It can lead to depression, irritability and aggressiveness, sleep disorders and loss of appetite.
Treatment of gabapentin dependence
Gabapentin dependence should be treated in a specialized facility. In addition to restoring physical health and normalizing the functionality of important organ systems, working with a psychotherapist is of great importance.
One should not try to convince a drug addict of the harmfulness of pharmacological agents. Only long-term psychotherapy followed by a period of rehabilitation can give hope for a cure.
Bolonkin Andrey Vladimirovich - psychiatrist, psychiatrist-narcologist, psychotherapist. He has more than 17 years of experience in the treatment of addiction, mental and psychosomatic disorders and borderline disorders.
Treating addiction is a complex and multi-step process. If your loved ones need help treating alcohol or drug addiction, make an appointment for a free consultation at the Zdravnitsa Professional Treatment and Rehabilitation Center by calling 8-800-200-27-23. We will create a rehabilitation plan and provide professional support to help you through the stages of recovery.
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